Serevent Inhaler (Salmeterol, Neovent)
Serevent Inhaler is used in adults and children with the need for regular use of bronchodilators, as well as to prevent nighttime symptoms and daytime symptoms caused by reversible airway obstruction (before exercise or unavoidable contact with the allergen), as part of combination therapy.Adults:
Reversible airflow obstruction with
bronchial asthma;
chronic bronchitis.
In patients with asthma onset of action Serevent Inhaler (increase in forced expiratory volume in 1 second (FEV1)> 15%) observed after 10-20 minutes after inhalation. The full therapeutic effect occurs within a few days of regular use Serevent. Step salmeterol continued for 12 hours. This is especially true for patients with nocturnal symptoms of asthma, COPD and chronic bronchitis, as well as to prevent asthma attacks caused by exercise.
Serevent Inhaler acts locally in the lung; its concentration in blood plasma reaches the therapeutic range. Available data on the pharmacokinetics of salmeterol are limited due to the fact that the determination of salmeterol in plasma is technically difficult; salmeterol concentration in plasma after dose inhalation Serevent very low (maximum concentration of 200 pg / ml or less). Excreted in the bile through the gastrointestinal tract, mainly in the form of a hydroxylated metabolite.